Noninvasive Glucometers in Development
1. AgaMatrix
http://www.agamatrix.com
2. AiMedics Pty Ltd
http://www.aimedics.com
3. Biopeak Corporation ( Fusion Spectroscopy Platform)
http://www.biopeak.com
4. Calisto Medical Inc.
http://www.calistomedical.com/eng/?p=main
5. CIBA Vision in Atlanta, Georgia, the eye care unit of Novartis AG, may be developing contact lenses that not only
correct vision but also painlessly measure blood glucose. The CIBA Vision site, however, does not mention it.
6. Diramed LLC in Carroll, Ohio, is developing a noninvasive blood glucose monitoring system. The company's
technology is infrared.
7. Fluent Biomedical Corp. Fluent is starting with spectroscopic techniques and signal analysis methods already
well-demonstrated to predict in vivo blood glucose levels noninvasively and accurately and adding proprietary new
nanotechnology-driven optical sources and newly enabled powerful calibration and error-checking methods to create
compact, reliable and calibration-free systems.
8. Futrex Inc. in Gaithersburg, Maryland, heavily promoted its "Dream Beam Analyzer," a small, portable,
noninvasive blood glucose measurement instrument. It promised to be the holy grail of blood glucose testing for
diabetes—if and when it becomes available. It's not here yet. In fact, its Web site doesn't even mention it any more.
http://www.futrex.com/
9. GlucoLight Corporation in Bethlehem, Pennsylvania. GlucoLight's unique optical approach, microscatter
technology, is based on patented technologies in the area of optical coherence tomography and low coherence
interferometry. There is a working prototype with published clinical data on healthy volunteers. The company's first
product, due late 2005, will be a "PDA size" noninvasive glucose monitor. They plan to submit this device to the FDA for
market clearance as an example for their corporate partners. The second generation product version will be the size of a
large sports watch and will provide continuous glucose monitoring The URL is
http://www.glucolight.com
10. Glucon Medical Ltd in Boulder, Colorado. Device gets its blood glucose measurements directly from inside the
blood vessels. It uses photoacoustic waves originating in the blood vessel to calculate the concentration of glucose in the
blood vessel. The URL is
http://www.glucon.com/
11. GluMetrics LLC in Marina, California, has developed a novel optical glucose sensor that could be used to
provide continuous monitoring of glucose levels. Its core technology, GluGlow, is a glucose-sensing polymer that has a
broad range of applications in clinical medicine. This chemical complex glows in the presence of glucose. This technology
can be used to measure blood sugar without the use of enzyme-based chemical reactions, which have been the basis of
legacy technology and which are plagued by instability and sensitivity to body chemistry. The URL is
http://www.Glumetrics.com. See also
http://www.medicalnewstoday.com/index.php?newsid=6673
12. Hitachi Ltd. The device is intended to compute blood glucose levels by using special sensors to detect
physiological parameters related to the body's metabolism, such as thermal energy, oxygen supply, and blood flow. The
company plans for the device to go on sale in 2005. The URL is
http://www.hitachi.com/New/cnews/040223.html
13. Infratec Inc. in Wilton, Connecticut, is developing a hand-held device that is inserted in the ear to measure
blood glucose levels noninvasively. It isolates and measures blood glucose levels from the eardrum using the body's
natural heat emission, or thermal radiation. The method and instrument are based on the discovery that natural mid-
infrared body emissions change, depending on the glucose concentration of the tissue. It is simply placed in the ear,
much like an ear thermometer, for about 10 seconds. No blood is drawn. The first published clinical study of this device
appears in the December 2002 issue of Diabetes Care, pp. 2268-75. The full text of the article is on-line at http://care.
diabetesjournals.org/cgi/content/full/25/12/2268.
14. InLight Solutions Inc.
http://www.inlightsolutions.com/
15. Integrity Applications in Ashkelon, Israel, hopes to introduce the first, real noninvasive device, the GlucoTrack.
The device will be the first capable of both singular and continuous measurements. GlucoTrack will be the only device
that uses different techniques simultaneously in order to increase reliability: ultrasound, conductivity, and heat capacity.
It tests on the ear with an ear ring.
http://www.integrity-app.com
16. LifeTrac Systems Inc. in Biddeford, Maine. The company says that it has contracted with a major medical
device manufacturer to produce a completely redesigned, miniaturized, production-grade prototype of their meter. The
new prototype will replace the hand-built units currently in use, making the device suitable for production and to prepare
for FDA approval. The SugarTrac uses near-infrared spectroscopy. But the summer 2005 issue of Voice of the Diabetic
has a disturbing article about this company, “What Happened to the SugarTrac?” The article is online at http://www.nfb.
org/vod/vodsum0520.htm
Website: http://www.sugartrac.com/
17. LighTouch Medical Inc. in New Hope, Pennsylvania, hopes to begin the FDA approval process by the end of
2002 and secure approval for a home use device that will be a safe, painless, noninvasive substitute for the finger-stick
method. The company's patented technology relies on a combination of Raman based spectroscopy and a proprietary
tissue modulation process to make direct blood glucose measurements.
http://www.lightouchmedical.com/
18. MedOptix Inc. in Cupertino, California, has developed "totally noninvasive blood glucose monitoring" system —
a patented new optical technology, known as ReSense Technology, based on mid-infrared (MIR) light reflection from the
skin surface. MedOptix is currently conducting initial clinical studies with diabetic subjects at multiple sites in California
using prototype ReSense devices.
http://www.medoptix.com
19. NIR Diagnostics Inc. in Campbellville, Ontario, Canada (formerly known as CME Telemetrix Inc. in Waterloo,
Ontario), says its "primary research goal...remains the completion of GlucoNIR, a diagnostic device for non-invasive
monitoring of glucose levels. " When the company was still known as CME Telemetrix it said that it was using near
infrared light.
http://www.cmetele.com/
20. OrSense Ltd., based in Rehovot, Israel, is dedicated to the pioneering and development of noninvasive
monitors of blood analytes such as glucose, hemoglobin, and cholesterol (innovative electro-optical technology). The
process involves stopping the flow of blood at the index finger by pressuring it gently, and then examining it with an
optical probe using sophisticated algorithms.
http://www.orsense.com/home.html
21. Pindi Products, based in Reno, Nevada, is focusing on developing a compact, pain-free noninvasive blood
glucose monitor.
http://www.pindi.com/
22. PreciSense in Horsholm, Denmark, says that its PreciSense System utilizes Fluorescence Resonance Energy
Transfer, which is directly related to the concentration of glucose. The PreciSense meter will be noninvasive and
continuous.
http://www.precisense.dk
23. Samsung Fine Chemicals Co. Ltd. The TouchTrak Pro 200 uses a noninvasive electromagnetic radiant ray
and is for hospital use. Samsung said that they are also developing a personal use meter, the TouchTrak HC 300.
Samsung no longer has any information about its TouchTrak meters on-line. However, a German site has a picture of the
TouchTrak Pro 200 at http://www.diabetiker-mailbox.com/bz/a3_834.html
24. Sensys Medical (formerly known as Instrumentation Metrics Inc.) in Chandler, Arizona (near-infrared technology)
http://www.sensysmedical.com/home.html
25. TecMed Inc. in Albuquerque, New Mexico. (electro-optical device). TecMed's technological approach is known
as "polarimetry," the science of measuring the rotation of the plane of polarized light.
http://www.tecmed.com 26. Visual Pathways Inc. in Prescott, Arizona. Designing the GlucoScope monitor. People
with diabetes will be able to look into something like a small pair of binoculars and activate it with the press of a button. In
a few seconds your blood glucose concentration will be displayed.
http://www.vispath.com/glucoscope.html
1. AgaMatrix
http://www.agamatrix.com
2. AiMedics Pty Ltd
http://www.aimedics.com
3. Biopeak Corporation ( Fusion Spectroscopy Platform)
http://www.biopeak.com
4. Calisto Medical Inc.
http://www.calistomedical.com/eng/?p=main
5. CIBA Vision in Atlanta, Georgia, the eye care unit of Novartis AG, may be developing contact lenses that not only
correct vision but also painlessly measure blood glucose. The CIBA Vision site, however, does not mention it.
6. Diramed LLC in Carroll, Ohio, is developing a noninvasive blood glucose monitoring system. The company's
technology is infrared.
7. Fluent Biomedical Corp. Fluent is starting with spectroscopic techniques and signal analysis methods already
well-demonstrated to predict in vivo blood glucose levels noninvasively and accurately and adding proprietary new
nanotechnology-driven optical sources and newly enabled powerful calibration and error-checking methods to create
compact, reliable and calibration-free systems.
8. Futrex Inc. in Gaithersburg, Maryland, heavily promoted its "Dream Beam Analyzer," a small, portable,
noninvasive blood glucose measurement instrument. It promised to be the holy grail of blood glucose testing for
diabetes—if and when it becomes available. It's not here yet. In fact, its Web site doesn't even mention it any more.
http://www.futrex.com/
9. GlucoLight Corporation in Bethlehem, Pennsylvania. GlucoLight's unique optical approach, microscatter
technology, is based on patented technologies in the area of optical coherence tomography and low coherence
interferometry. There is a working prototype with published clinical data on healthy volunteers. The company's first
product, due late 2005, will be a "PDA size" noninvasive glucose monitor. They plan to submit this device to the FDA for
market clearance as an example for their corporate partners. The second generation product version will be the size of a
large sports watch and will provide continuous glucose monitoring The URL is
http://www.glucolight.com
10. Glucon Medical Ltd in Boulder, Colorado. Device gets its blood glucose measurements directly from inside the
blood vessels. It uses photoacoustic waves originating in the blood vessel to calculate the concentration of glucose in the
blood vessel. The URL is
http://www.glucon.com/
11. GluMetrics LLC in Marina, California, has developed a novel optical glucose sensor that could be used to
provide continuous monitoring of glucose levels. Its core technology, GluGlow, is a glucose-sensing polymer that has a
broad range of applications in clinical medicine. This chemical complex glows in the presence of glucose. This technology
can be used to measure blood sugar without the use of enzyme-based chemical reactions, which have been the basis of
legacy technology and which are plagued by instability and sensitivity to body chemistry. The URL is
http://www.Glumetrics.com. See also
http://www.medicalnewstoday.com/index.php?newsid=6673
12. Hitachi Ltd. The device is intended to compute blood glucose levels by using special sensors to detect
physiological parameters related to the body's metabolism, such as thermal energy, oxygen supply, and blood flow. The
company plans for the device to go on sale in 2005. The URL is
http://www.hitachi.com/New/cnews/040223.html
13. Infratec Inc. in Wilton, Connecticut, is developing a hand-held device that is inserted in the ear to measure
blood glucose levels noninvasively. It isolates and measures blood glucose levels from the eardrum using the body's
natural heat emission, or thermal radiation. The method and instrument are based on the discovery that natural mid-
infrared body emissions change, depending on the glucose concentration of the tissue. It is simply placed in the ear,
much like an ear thermometer, for about 10 seconds. No blood is drawn. The first published clinical study of this device
appears in the December 2002 issue of Diabetes Care, pp. 2268-75. The full text of the article is on-line at http://care.
diabetesjournals.org/cgi/content/full/25/12/2268.
14. InLight Solutions Inc.
http://www.inlightsolutions.com/
15. Integrity Applications in Ashkelon, Israel, hopes to introduce the first, real noninvasive device, the GlucoTrack.
The device will be the first capable of both singular and continuous measurements. GlucoTrack will be the only device
that uses different techniques simultaneously in order to increase reliability: ultrasound, conductivity, and heat capacity.
It tests on the ear with an ear ring.
http://www.integrity-app.com
16. LifeTrac Systems Inc. in Biddeford, Maine. The company says that it has contracted with a major medical
device manufacturer to produce a completely redesigned, miniaturized, production-grade prototype of their meter. The
new prototype will replace the hand-built units currently in use, making the device suitable for production and to prepare
for FDA approval. The SugarTrac uses near-infrared spectroscopy. But the summer 2005 issue of Voice of the Diabetic
has a disturbing article about this company, “What Happened to the SugarTrac?” The article is online at http://www.nfb.
org/vod/vodsum0520.htm
Website: http://www.sugartrac.com/
17. LighTouch Medical Inc. in New Hope, Pennsylvania, hopes to begin the FDA approval process by the end of
2002 and secure approval for a home use device that will be a safe, painless, noninvasive substitute for the finger-stick
method. The company's patented technology relies on a combination of Raman based spectroscopy and a proprietary
tissue modulation process to make direct blood glucose measurements.
http://www.lightouchmedical.com/
18. MedOptix Inc. in Cupertino, California, has developed "totally noninvasive blood glucose monitoring" system —
a patented new optical technology, known as ReSense Technology, based on mid-infrared (MIR) light reflection from the
skin surface. MedOptix is currently conducting initial clinical studies with diabetic subjects at multiple sites in California
using prototype ReSense devices.
http://www.medoptix.com
19. NIR Diagnostics Inc. in Campbellville, Ontario, Canada (formerly known as CME Telemetrix Inc. in Waterloo,
Ontario), says its "primary research goal...remains the completion of GlucoNIR, a diagnostic device for non-invasive
monitoring of glucose levels. " When the company was still known as CME Telemetrix it said that it was using near
infrared light.
http://www.cmetele.com/
20. OrSense Ltd., based in Rehovot, Israel, is dedicated to the pioneering and development of noninvasive
monitors of blood analytes such as glucose, hemoglobin, and cholesterol (innovative electro-optical technology). The
process involves stopping the flow of blood at the index finger by pressuring it gently, and then examining it with an
optical probe using sophisticated algorithms.
http://www.orsense.com/home.html
21. Pindi Products, based in Reno, Nevada, is focusing on developing a compact, pain-free noninvasive blood
glucose monitor.
http://www.pindi.com/
22. PreciSense in Horsholm, Denmark, says that its PreciSense System utilizes Fluorescence Resonance Energy
Transfer, which is directly related to the concentration of glucose. The PreciSense meter will be noninvasive and
continuous.
http://www.precisense.dk
23. Samsung Fine Chemicals Co. Ltd. The TouchTrak Pro 200 uses a noninvasive electromagnetic radiant ray
and is for hospital use. Samsung said that they are also developing a personal use meter, the TouchTrak HC 300.
Samsung no longer has any information about its TouchTrak meters on-line. However, a German site has a picture of the
TouchTrak Pro 200 at http://www.diabetiker-mailbox.com/bz/a3_834.html
24. Sensys Medical (formerly known as Instrumentation Metrics Inc.) in Chandler, Arizona (near-infrared technology)
http://www.sensysmedical.com/home.html
25. TecMed Inc. in Albuquerque, New Mexico. (electro-optical device). TecMed's technological approach is known
as "polarimetry," the science of measuring the rotation of the plane of polarized light.
http://www.tecmed.com 26. Visual Pathways Inc. in Prescott, Arizona. Designing the GlucoScope monitor. People
with diabetes will be able to look into something like a small pair of binoculars and activate it with the press of a button. In
a few seconds your blood glucose concentration will be displayed.
http://www.vispath.com/glucoscope.html
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